Applied Pharmacokinetics & Pharmacodynamics: Principles of Therapeutic Drug MonitoringMichael E. Burton Used by practitioners, educators, scientists, and students as a definitive reference source on pharmacokinetics, pharmacodynamics, and therapeutic drug monitoring, the fully updated Fourth Edition is a rigorous, yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and relevant pharmacotherapeutic data to optimize drug therapy for individual patients. |
Contents
Drug Disposition | 187 |
Special Pharmacokinetic | 213 |
Special Pharmacokinetic Considerations | 231 |
Dietary Influences on Drug Disposition | 242 |
3 | 259 |
Lalonde | 328 |
Microbiologic Clinical and Economic | 341 |
8 | 357 |
Clinical Pharmacokinetics of Oral 27 HeparinUFH and LMWH | 637 |
Bauman Harumi Takahashi and Robert J Cipolle and Eleanor S Pollak | 715 |
Nonsteroidal AntiInflammatory Drugs | 752 |
Rebeccah J Collins | 781 |
Atholl Johnston and David W Holt | 798 |
Laurence Chan 32 Antipsychotics | 813 |
Mycophenolic Acid 563 | 839 |
| 849 | |
Common terms and phrases
absorption activity administration adults albumin allele altered aminoglycoside amiodarone antibiotics Antimicrob Agents Chemother assay AUIC bioavailability Biopharm carbamazepine centrations changes CLcr Clin Pharmacokinet Clin Pharmacol Ther clinical cokinetics compared creatinine clearance decreased dialysis digoxin disease disopyramide dosage regimens dose drug concentrations drug interactions drug metabolism drug monitoring effect elimination Emax enzyme estimated evaluation excretion gentamicin half-life hepatic human increase indinavir infants Infect inhibition inhibitors intravenous kinetics liver macokinetics measured metabolites method mg/L nelfinavir nephrotoxicity netics obese oral patients peak Pediatr Phar Pharm pharmacodynamic pharmacoki pharmacologic phenytoin phenytoin concentration plasma concentrations plasma protein binding polymorphisms predicted propranolol quinidine ratio receptor renal function response result ritonavir saquinavir serum concentrations serum digoxin steady-state studies substrates theophylline Ther Drug Monit therapeutic range therapy tients tion tissue tobramycin toxicity unbound fraction valproic acid values vancomycin variability vitro Vmax volume of distribution zidovudine µg/mL