Benchmarks: Alternative Methods in ToxicologyMyron A. Mehlman |
Contents
PREFACE | 1 |
METHODOLOGIES FOR INTERPRETATION OF SHORTTERM | 15 |
CASE THE COMPUTERAUTOMATED STRUCTURE EVALUATION | 29 |
Copyright | |
5 other sections not shown
Common terms and phrases
accuracy acid activity acute toxicity testing alternative animal bioassay animal testing Appl approach battery bioassay Biochem biological cancer carbon tetrachloride carcinogenicity carcinogenicity assay cell lines Chem classification compounds concentration correlation cytotoxicity dermal detect developmental toxicity dose Draize Draize test drug embryo embryo culture endpoints Ennever and Rosenkranz equation estimate evaluation experimental exposure eye irritation tests false positives FHSA genotoxic hazard Health hepatocytes hepatotoxicity human carcinogens identified KLOPMAN laboratory LDso limb bud liver Mary Ann Liebert materials mechanisms metabolism methods mg/kg mouse Mutagen Mutation nephrotoxicity non-carcinogens number of animals ocular irritation organ pharmacokinetic pharmacokinetic model Pharmacol physiological models potency predict primary cultures proximal tubule rat hepatocytes regulatory response risk assessment rodent SAR models sensitive short-term tests species STACEY STTs studies Table teratogenesis teratogenic Teratology test agent test substance test system tissue Toxicol Toxicology validation vitro screens vitro systems vitro tests vivo xenobiotic Zbinden