Binding and Dissociation Kinetics for Different Biosensor Applications Using FractalsThe application of biosensors is expanding in different areas. These are portable and convenient devices that permit the rapid, accurate, and reliable detection of analytes of interest present either in the atmosphere or in aqueous or in liquid phases. The detection of glucose levels in blood for the effective management of diabetes is one. Though different biosensors have been designed for an increasing number of applications, the kinetics of binding (and dissociation) of analytes by the receptors on the biosensor surfaces has not been given enough attention in the open literature. This is a very important area of investigation since it significantly impacts biosensor performance parameters such as stability, sensitivity, selectivity, response time, regenerability, etc. Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals addresses this critical need besides helping to correct or demonstrate the need to modify the present software available with commercial biosensors that determines the kinetics of analyte-receptor reactions on biosensor surfaces. * first book to provide detailed kinetic analysis of the binding and dissociation reactions that are occuring on the biosensor surface * addresses the area of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces * provides physical insights into reactions occuring on biosensor surfaces |
Contents
| 1 | |
| 17 | |
Chapter 3 Fractal Analysis of Toxin and Pathogen Detection on Biosensor Surfaces | 31 |
Chapter 4 Fractal Binding and Dissociation Kinetics of HeartRelated Compounds on Biosensor Surfaces | 57 |
Chapter 5 Fractal Analysis of Binding and Dissociation Kinetics and Interactions of Cancer Markers on Biosensor Surfaces | 93 |
Chapter 6 Fractal Analysis of Binding and Dissociation of Autoimmune Disease Markers on Biosensor Surfaces | 111 |
Chapter 7 Fractal Binding and Dissociation Kinetics of Prion Proteins on Biosensor Surfaces | 137 |
Chapter 8 Detection of Environmental Contaminants by Biosensors | 161 |
Chapter 9 Fractal Analysis of Proteins Involved in Drug Design on Biosensor Surfaces | 199 |
Chapter 10 SolGel Biosensor Applications | 219 |
Chapter 11 Novel Biosensing Methods | 243 |
Chapter 12 Fractal Analysis of the Binding and Dissociation of Different Compounds on Biosensor Surfaces | 273 |
Chapter 13 Market Size and Economics for Biosensors | 319 |
| 343 | |
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Binding and Dissociation Kinetics for Different Biosensor Applications Using ... Ajit Sadana No preview available - 2006 |
Common terms and phrases
adequate to describe adequately describe affinity K1 analysis are given analysis is adequate analysis is required Analyte in solution Analytical Chemistry analyze the binding antibody Biacore binding and dissociation binding kinetics binding rate coefficient biosensor surface C1q concentration CCR5 cholesterol coefficient k concentration in solution concentration range decrease degree of heterogeneity dependence exhibited describe the binding detection developed Df1 and Df2 Df2 Dfd Dfd2 diffusion dissociation kinetics dissociation phase dissociation rate coefficient dual-fractal analysis Figure fractal analysis fractal dimension Df g/ml given in Table Havlin hybridization immobilized k1 and k2 kalata leptin leptin concentration optical fiber order of dependence points are available points would lead protein putrescine Quattro Pro rate coefficient k2 ratio of fractal receptor reliable fit required to adequately Sadana ScFv2 concentration sensitive sensor chip surface show the binding show the increase single-fractal analysis sol–gel SPR biosensor surface plasmon resonance three data points VEGF
Popular passages
Page 24 - Df,d is the fractal dimension of the surface for the dissociation step. td represents the start of the dissociation step. This corresponds to the highest concentration of the analyte-receptor on the surface.