Biochemistry of ZincBiochemistry of Zinc critically examines these and other significant advances in basic research and relates them to the biological results of insufficient amounts of zinc in the body. This comprehensive text describes several recently discovered effects of zinc deficiency - such as anergy, and decreased levels of IL-2 and IL-1 production, natural killer cell activity, and active thymulin peptide - and assesses their clinical implications in the treatment of zinc-related immune disorders. It covers all the vital biochemical information on zinc and its functions, including its interactions with enzymes, hormones, lipid metabolism, cells, neurobiology, and other micronutrients. The book also discusses the relevant historical aspects of zinc and features an informative chapter on techniques for measuring zinc in biological samples, using atomic absorption spectrophotometry. |
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abnormal acrodermatitis enteropathica Adapted with permission alkaline phosphatase amino acids anemia animals assay binding Biochem Biol brain Brewer calmodulin catalyzes Clin clinical concentration copper Cunnane decreased deficiency of zinc diet dietary zinc domain Dreosti dwarfism effect of zinc enzyme erythrocytes excretion function GAL4 protein gene geophagia growth retardation hormone human subjects hypogonadism immune increased induced inhibited insulin interaction intestinal iron ligands Liss liver lymphocytes Meftah membrane metal ions metallothionein mg/day mice normal nucleoside nucleoside phosphorylase Nutr nutritional Oberleas observed oral zinc pair-fed patients penicillamine permission from Prasad plasma platelets polymerase Proc prolactin protein Rabbani receptor Reprinted with permission result of zinc RNA polymerase role of zinc Sandstead sickle cell significantly synthesis testosterone tissues Trace Elements uptake vitamin vitro Wilson's disease zinc absorption zinc content zinc deficiency zinc intake zinc restriction zinc status zinc supplementation zinc therapy zinc-deficient rats Zn2+