The Biological Monitoring of Exposure to Chemicals, Volume 1: Organic CompoundsMat H. Ho, H. K. Dillon Provided here is an assessment of current applications and future directions for the biological monitoring of occupational exposure to chemicals (with the emphasis on organic chemicals). The book begins with an introduction and thorough review of the principles of biological monitoring, and reviews the investigations of scientists from all over the world dealing with specific applications in biological monitoring. Techniques that may provide great potential for the application of biological monitoring to the early detection or prevention of carcinogens are surveyed, and in addition, the book includes a discussion of the fluorescence method as a potential monitoring technique for early detection of occupational cancers. |
Contents
GENERAL PRINCIPLES FOR BIOLOGICAL MONITORING | 1 |
BIOLOGICAL MONITORING AND HEALTH SURVEILLANCE | 3 |
IMPORTANT CONSIDERATIONS IN THE DEVELOPMENT | 17 |
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1,1,1-trichloroethane 2-Methylpentane acid in urine activity alkyl phosphates alveolar air alveolar concentration analysis analyzed Arch benzene biological monitoring biotransformation blood samples Brugnone C₂H,O cells CH,O Chem chemicals cholinesterase coefficient compounds correlation creatinine cyclohexane D-glucaric acid demeton derivatization detection determination effects elimination Environ environmental enzyme erythrocyte esters expired air exposure concentration exposure to styrene exposure to toluene Figure gas chromatograph Health hippuric acid human hydrolysis Industrial inhaled kinetics laboratory levels liver mandelic acid measured mercapturates metabolism metabolites methanol method methyl mg/L mg/m³ monitoring of exposure n-hexane o-cresol obtained occupational exposure OXIDATION parameters parathion Perbellini pesticides phenol phenylglyoxylic acid phorate phosphorothionates plasma porphyrins posure reaction reported serum soluble solvents styrene substance Table thioether tissue toluene toluene exposure toxic Toxicol trichloroethylene uptake urinary excretion urine urine collected urine samples vapors workers exposed workshift xylene µg/L µg/mL