Biomaterials for Surgical Operation

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Springer Science & Business Media, Dec 21, 2011 - Medical - 214 pages

Biomaterials for Surgical Operation offers a review of the latest advances made in developing bioabsorbable devices for surgical operations which include surgical adhesives (sealants), barriers for the prevention of tissue adhesion, polymers for fractured bone fixation, growth factors for the promotion of wound healing, and sutures. Over the years, many descriptions of biomaterials have appeared in academic journals and books, but most of them have been devoted to limited clinical areas. This is in marked contrast with this volume which covers a wide range of bioabsorbable devices used in surgery from a practical point of view. The currently applied polymeric devices are critical in surgery, but all involve serious problems due to their poor performance. For instance, fibrin glue, the most widely used surgical sealant, can produce only a weak gel with low adhesive strength to tissues, accentuating the limited effectiveness of current treatment options. Likewise, the currently available barrier membranes cannot fully prevent tissue adhesion at the acceptable level and are, moreover, not easy to handle with endoscopes due to their poor mechanical properties.

Biomaterials for Surgical Operation is aimed at those who are interested in expanding their knowledge of how the problems associated with the currently used devices for surgical operation can be solved. It primarily focuses on the absorbable biomaterials which are the main components of these medical devices.

 

Contents

Chapter 1 Introduction
1
Chapter 2 Biological Events Associated with Surgical Operation
7
Chapter 3 Bioabsorbable Polymers
18
Chapter 4 Sealants Adhesives to Prevent Bleeding
39
Chapter 5 Barriers to Prevent Tissue Adhesion
91
Chapter 6 Devices for Bone Fixation
131
Chapter 7 Growth Factors for Promoting Wound Healing
145
Chapter 8 Sutures for Wound Closure
189
Chapter 9 Conclusions
199
Index
204
About the Authors
211
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About the author (2011)

Shuko Suzuki obtained PhD degree in polymer chemistry from Queensland University of Technology, Australia. After JSPS fellowship at Nara Medical University, she joined GUNZE Ltd., Japan, and is currently working as research fellow at Nara Medical University.

Yoshito Ikada has over forty year’s experience as a professor at a number of universities in Japan and China in the field of biomedicine. Currently at Nara Medical University and he is also Emeritus Professor at Kyoto University and Guest Professor at Peking University. He has received the Prize of Japanese Society for Biomaterials and was President of the Japanese Society for Biomaterials for four years. He was also Chairman of National project, “Tissue Engineering” by Japan Society for the Promotion of Science. He authored “Tissue Engineering: Fundamentals and Applications” (Academic Press, 2006).

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