Chemoattractant Ligands and Their ReceptorsChemoattractant Ligands and Their Receptors succinctly summarizes cutting-edge research in the important area of chemoattraction in immunology. It explains how chemoattractant molecules mobilize immune cells to ward off attack by invading pathogens, both at a molecular and at a cellular level. Written by acknowledged experts in the field, it contains detailed molecular and structural information on each of the major chemoattractants and their receptors. Its unique multidisciplinary approach encompasses biology, immunology, protein chemistry, and molecular biology. A time-saving reference for both researchers and students. |
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Acad adhesion affinity amino acid antigen Baggiolini basophils Biochem Biol biological blood C-C chemokines calcium cDNA cell line Chem chemokine binding chemokine receptors chemotactic factor chemotaxis Clark-Lewis cloned cytokine DARC dimer disease domain Duffy ECRF3 effects encoding endothelial cells eosinophils erythrocytes expression fibroblasts Figure fMLF functional G protein G protein-coupled receptors gene high-affinity homolog Horuk human monocytes human neutrophils identified IL-8 binding IL-8 receptor Immunol induced inflammation inhibit interaction interleukin-8 interleukin-8 receptor intracellular kinase leukocyte leukotriene ligand lung lymphocytes macrophage inflammatory protein mediated melanoma membrane MGSA MGSA/GRO migration molecular molecules monocyte chemoattractant monocyte chemoattractant protein-1 monocyte chemotactic monomer mouse mRNA murine mutations N-terminal Natl neutrophil activating neutrophils peptide phagocytes phospholipase platelet potential protein-1 protein-coupled receptors rabbit RANTES receptor binding region regulation residues response role Schall sequence signal transduction specific stem cell stimulation structure studies subunit suggest tissue transcription transfected tumor vitro vivo