Diuretics--chemistry, Pharmacology, and MedicineEdward J. Cragoe |
Contents
STRUCTURE OF THE KIDNEYS | 20 |
CONCENTRATION AND DILUTION OF THE URINE | 31 |
DIURESIS AND DIURETICS | 38 |
Copyright | |
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acid action addition administration agents aldosterone amiloride analogs animals antihypertensive appears assay blood carbonic anhydrase changes Chem Clin clinical collecting compared compounds concentration COOH decrease derivatives described distal diuresis diuretic activity dogs dose drug effect electrolyte enhanced evaluated excretion exhibited Figure flow fluid function furosemide given glucose H H H hydrochlorothiazide hypertension inactive increase influence inhibition inhibitors involved kidney lead less levels loop mechanism mefruside methyl mg/kg moiety natriuretic nephron nitrogen normal observed occurs oral Patent Pharmacol Pharmacology plasma possess potency produced properties proximal rats reabsorption recently reduced relatively renal replacement reported response ring saluretic Score secretion seen shown shows significant similar species structure substituents suggest sulfamoyl Table Ther thiazides transport tubular tubule U.S. Patent urinary urine values various volume