From Premature Gray Hair to Helicase-- Werner Syndrome: Implications for Aging and CancerMakoto Goto, Robert W. Miller |
Contents
A Brief History of Research on the Werner Syndrome G M MARTIN | 1 |
X | 8 |
The Search for the Werner Syndrome Gene D DRAYNA | 11 |
Copyright | |
15 other sections not shown
Common terms and phrases
4NQO abnormalities Acad aging process atherosclerosis atrophy Biol Bloom syndrome Cancer cell lines cellular chromosome clinical clonal cloning Cockayne syndrome coli collagen connective tissue cultured Cytogenet diabetes mellitus disease DNA helicase drome Epstein exonuclease fibroblasts FL cells function Furuichi genetic instability genomic Goto haplotype helicase activity helicase gene human RecQ helicases increased Japan Japanese Kitao LCLs linkage lymphocytes markers Martin Matsumoto melanoma Monnat mutations Nakura Natl neoplasms neurological normal aging Oshima osteosarcoma pathologic patients with Werner patients with WS phenotypes polymorphic premature aging progeria progeroid syndromes protein recombination RecQ helicase RecQ helicase deficiency replication reported Rothmund-Thomson syndrome sarcoma senescence sequence sgs1 mutant Shimamoto skin strand studies Sugimoto syndrome patients telomerase telomerase activity telomere thyroid carcinoma tion transcription translocation tumor unwinding vitro vivo Werner syndrome Werner's syn Werner's syndrome gene WRN gene WRN helicase WRN mutations WRN protein WS cells WS patients