Gene Expression in the Central Nervous SystemAlbert C. H. Yu Gene expression is an active ongoing process that maintains a functional CNS, as proteins are being made on a continual basis. Processes such as learning and memory, nerve cell repair and regeneration and its response to stress are critically dependent on gene expression. This volume highlights the role of gene expression in normal CNS function, and presents many research methods at the cutting edge of neuroscience, which will provide insight into therapeutic approaches through which the control of gene expression may be used in the treatment of many nervous system diseases. |
Contents
Signal Transduction and Gene Expression | 53 |
Development Differentiation and Aging | 127 |
Diseases and Injury | 217 |
Other editions - View all
Gene Expression in the Central Nervous System A.C.H. Yu,L.F. Eng,U.J. McMahan,H. Schulman,E.M. Shooter,A. Stadlin Limited preview - 1995 |
Common terms and phrases
Acad activity Aga-IVA antibody astrocytes axons BDNF binding Biol Brain Res c-fos Ca2+ channels calcium calmodulin CaM kinase cDNA cell line cellular cerebral cloning CNTF cortex cortical culture cytokines dentate gyrus differentiation disease domain encoding function gene expression genetic GFAP glial cells growth factor hippocampal increase induced inhibition InsP3 interactions intracellular ischemia isoform K+ channels layer lesions levels mammalian membrane microglia molecular molecules mouse mRNA mRNA expression mutant mutant mice myelin Natl nerve growth nerve growth factor nervous system neural neurofibromin neurons Neurosci neurotrophic factor neurotrophins NMDA normal oligodendrocytes opioid P-type peptide peripheral phosphorylation PLA2 PLP gene postsynaptic potentiation prion Proc protein kinase proteolipid rat brain receptor region regulation release response role Schulman Schwann cells Science scrapie sequence signal slices specific stimulation studies subunits synaptic vesicle tion tissue trans transcription transport trkB vitro vivo