Health Effects of Alpha-emitting Particles in the Respiratory Tract: Report of Ad Hoc Committee on "Hot Particles" of the Advisory Committee on the Biological Effects of Ionizing Radiations |
Other editions - View all
Common terms and phrases
aerosol Albert alpha irradiation alpha particles alpha radiation alveolar cells alveoli average Battelle group Battelle Pacific Northwest beagle Beagle Dogs Biological Effects bronchi bronchiolo-alveolar cancer death risk Carcinogenesis carcinogenic Casarett Clara cells clearance Cochran and Tamplin cytoplasm density diameter distribution electrons epithelial cells epithelium estimate experimental animals experiments exposed exposure hair follicles hamsters Health Phys Hemangiosarcoma hot particle induction Inhaled Particles inhaled plutonium insoluble International intratracheal ionizing radiation lesions lethal lung cancers Lovelace Foundation lung burden lung cancer lung cancer death lung cancer risk Lung Dose lung tissue lung tumors macrophages Medical Center Member National Academy neoplasia nucleus oxide Pacific Northwest Pacific Northwest Laboratory Physics plutonium particles pulmonary neoplasia PuO2 Radiation Biology radiation dose Radiation Protection Radiation Research radioactive Radiological radionuclides rat skin relatively Report Research Council respiratory tract Richland Sciences soluble specific activity studies Table tion transuranic elements uranium W. J. Bair
Popular passages
Page B-16 - Medical Research Branch, Division of Biology and Medicine. US Atomic Energy Commission, Washington, DC 1965 Senior Scientist, Biology Department, Pacific Northwest Laboratories, Battelle Memorial Institute, Richland.
Page A-77 - Huebner, RJ, Pereira, HG, Allison, AC, Hollinshead, AC, and Turner, HC: Production of type-specific C antigen in virusfree hamster tumor cells induced by adenovirus Type 12. Proc. Nat. Acad. Sci.
Page A-15 - Pulmonary Deposition and Retention of Inhaled Aerosols," Academic Press, New York, 1964.
Page A-17 - Pathogenesis and reversibility of the pulmonary lesions of oxygen toxicity in monkeys. II. Ultrastructural and morphometric studies.
Page 5 - ... Annual Report for 1965 In the Biological Sciences, BNWL280, 1956, pp. 13-14. Intense localized radiation of the subcutaneous and intraperitoneal tissue of animals by Pu-239 has also been shown to cause a high frequency of cancer induction **•**. Now what are these experiments trying to tell us? Certainly a reasonable interpretation of these experimental results is: when a critical architectural unit of a tissue (eg, a hair follicle) is irradiated at a sufficiently high dosage, the chance of...
Page A-18 - B. 1972. The effect of ascorbic acid on collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibroblasts. Arch. Biochem. Biophys. 152: 318-328.
Page 6 - Report.70 A. Occupational exposure The existing occupational exposure standard for uniform whole body irradiation is 5 rem/yr and for the lung, 15 rem/yr. the BEIR Report estimates that exposure of the whole body of an individual to 5 rem/yr would lead to a cancer risk between 4.5x10...
Page 5 - s lung model, a particle with an alpha activity between 0.02 pCi and 0.14 pCi is required to give a dose of 1000 rem/yr to irradiated lung tissue. For purposes of establishing a maximum permissible lung particle burden we will use 0.07 pCi from long half-lived (greater than one year) isotopes as the limiting alpha activity to qualify as a hot particle.
Page A-18 - MJ (1968). The ultrastructural basis of alveolar-capillary membrane permeability to peroxidase used as a tracer. J. Cell Biol.
Page A-16 - A comparative cytochemical study of microbodies (peroxisomes) in great alveolar cells of rodents, rabbit and monkey. J Histochem Cytochem 20:180.