Koch's remedy in relation specially to throat consumptionLea Brothers & Company, 1891 - 114 pages |
Common terms and phrases
admitted aged appearance aryepiglottic folds arytenoid cartilage bacilli Berlin centigramme Central London Throat changes Charité colour commenced contra-indication cough culosis December December 13 diagnosis dose dulness dysphagia dyspnoea Ear Hospital epiglottis evidence expectoration fauces fluid glands glottis gramme hæmoptysis healing Highest temperature hyperæmia improvement increase induced infiltration inflammation injection under Professor inter-arytenoid January Koch injections Koch's remedy Koch's treatment laryngeal phthisis laryngeal tuberculosis larynx Lennox Browne less lupus ment mucous membrane natural necrotic nodules normal nose November November 22 observed odynphagia pain patient pharynx phenomena phthisis physical signs posterior commissure posterior wall Professor Gerhardt Professor Krause pulmonary disease Pulse Pulse-tracing quantity râles reaction Resp right lung seen skin slight sputa sputum stenosis swelling swollen symptoms syphilis syringe thickening throat and larynx tion tissue treated treatment under Professor tuber tubercle bacilli tubercular laryngitis tuberculous ulceration Urine uvula ventricular band vocal cords
Popular passages
Page 51 - ... the guinea-pig. A new proof for the experimenter of the all-important law that experiment on animals is not conclusive, for the human patient proved extraordinarily more sensitive than the guinea-pig. As regards the effect of the remedy, a healthy guineapig will bear...
Page 104 - I succeeded, by the help of a 40 to 50 per cent, solution of glycerine, in extracting the active principle from the tubercle bacilli. My further experiments on animals, and finally on human beings, were made with liquid thus obtained ; and in this way also the liquid which I let other physicians have in order to repeat the experiments was obtained.
Page 43 - ... be cured as easily and quickly as the first attack. On the other hand, it seems possible that, as in other infectious diseases, patients once cured may retain their immunity ; but this, too, for the present, must remain an open question. In part, this may be assumed for other cases, when not too far advanced; but patients with large cavities, who suffer from complications caused, for instance, by the incursion of other pus-forming microorganisms into the cavities or by incurable pathological...
Page 44 - ... suffer from complications caused, for instance, by the incursion of other pus-forming microorganisms into the cavities or by incurable pathological changes in other organs will probably obtain lasting benefit from the remedy in only exceptional cases. Even such patients, however, were benefited for a time. This seems to prove that in their cases, too, the original tuberculous disease is influenced by the remedy in the same manner as in the other cases, but that we are unable to remove the necrotic...
Page 24 - This specific action of the remedy in these cases is less striking, but is as perceptible to eye and touch as are the local reactions in cases of tuberculosis of the glands, bones, joints, etc. In these cases swelling, increased sensibility, and redness of the...
Page 25 - I mentioned that after the subsidence of the swelling and decrease of the redness the lupus tissue does not return to its original condition, but that it is destroyed to a greater or less extent and disappears. Observation shows that in some parts this result is brought about by the diseased tissue be•coming necrotic, even after but one sufficiently large injection, and at a later stage it is thrown off as a dead mass.
Page 30 - At first the living tuberculous tissue must be caused to undergo necrosis, and then everything must be done to remove the dead tissue as soon as possible, as, for instance,, by surgical interference. Where this is not possible, and where the organism is unassisted in throwing off...
Page 105 - ... as it can withstand high temperatures, and in the dialyzer passes quickly and easily through the membrane. The quantity of active principle present in the extract is, in all probability, very small ; I estimate it at fractions of one per cent.
Page 43 - Objectively, even in these cases the expectoration decreased and the subjective condition improved. These experiences lead me to suppose that phthisis in the beginning can be cured with certainty by this remedy.
Page 103 - Finally it is thrown off, and a fiat ulcerated surface remains, which generally heals quickly and completely, without carrying infection to the neighbouring lymphatic glands. Thus the inoculated tubercle bacilli act quite differently on the skin of a healthy guineapig and on that of a tuberculous one. But this remarkable action does not belong exclusively to living tubercle bacilli, but also in the same degree to dead ones, whether killed by low temperatures of long duration, which I at first tried,...