Lymphangiogenesis in Cancer MetastasisSteven A. Stacker, Marc G. Achen Lymphangiogenesis and Cancer Metastasis introduces the new field of lymphatic vessel growth and development, and its relationship to the metastatic spread of cancer cells. The book covers all aspects of this new field from the fundamental role that protein growth factors and their receptors play in lymphangiogenesis to the potential application of these advances to cancer diagnosis and treatment. Other clinical aspects explored include the mechanisms and importance of lymph node metastasis, the role of the lymphatics in lymphangioleiomyomatosis and Kaposi’s sarcoma, and approaches for imaging lymphatics in cancer. The book also covers the innovative approaches taken by researchers to explore new roles for lymphatic vessel biology in the context of cancer. The information presented in this volume, which describes the revolutionary concepts of tumor lymphangiogenesis, will be of interest to all students, scientists and oncologists who are seeking to understand the complexities of tumor metastasis. Key Features:
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Contents
| 1 | |
Hogan | 8 |
INSIGHT INTO LYMPHATIC VASCULATURE DEVELOPMENT 11 | 10 |
NEW ANIMAL MODELS OF LYMPHANGIOGENESIS | 49 |
Institute of Pharmaceutical Sciences Swiss Federal Institute of Technology | 55 |
THE CLINICAL SIGNIFICANCE OF LYMPHNODE | 117 |
Zurich HCI H303 CH8093 Zurich Switzerland michael detmarpharma ethz | 118 |
LYMPHANGIOGENESIS AND IMAGING OF | 159 |
Teruhiko Sato | 185 |
KAPOSIS SARCOMA AND THE LYMPHATICS | 211 |
vii | 245 |