Manual of Laboratory Pharmacokinetics: Experiments in Biopharmaceutics, Biochemical Pharmacology, and Pharmacokinetics, with a Consideration of Relevant Instrumental and Chromatographic TechniquesProvides a wide range of reliable, straightforward experiments for training laboratory workers. Covers all relevant areas from instrumental and chromatographic techniques through chemical properties and theoretical pharmacokinetics to response studies. Uses readily available, important drug examples and discusses a wide variety of techniques, with emphasis on classical applications. Includes model data sheets. |
Contents
Absorption | 12 |
Assay of drug concentrations in biological fluids | 32 |
Physicochemical properties of drugs and dosage forms | 39 |
Copyright | |
10 other sections not shown
Common terms and phrases
absorbance absorption acid analysis apparatus application approximately aqueous assay assessment blood buffer Calculate calibration cells cent centrifuge changes chemical chromatography column compartment compounds concentration constant containing counting cuvette decay detector determination dilution dissolution distilled distribution dose drug equation ethanol excretion experiment extraction flasks flow fluid fluorescence give given glass glucose graph half-life imipramine included injection Introduction involved ionization kinetics Laboratory light liquid material mean measurement method minutes noradrenaline Note obtained occurs organic partition phase Pipette Place plasma plate plot powder Prepare Procedure protein radioactive ratio reaction reading reagent Record reference Remove sample scintillation separation sodium solution solvent specific spectrum standard studied suitable sulphadimidine tablets technique temperature tion Treatment tubes units urine usually values various vials volume wavelength µg ml-¹