Product Safety Evaluation Handbook, Second EditionShayne C. Gad "Provides comprehensive, single-source coverage of the latest toxicity testing requirements and methods for personal care products, industrial and agricultural chemicals, and consumer goods. Second Edition, contains a new chapter on toxicokinetic testing and modeling, offers the latest solutions to common problems in testing and risk assessment, supplies an updated bibliography and more than 1300 references-over 100 new to this edition, and more." |
Contents
| 3 | |
| 25 | |
Acute Systemic Toxicity Testing | 45 |
Evaluating Products for Their Potential to Cause Dermal and Ocular Irritation and Corrosion | 89 |
Predicting Dermal Hypersensitivity Responses | 125 |
Genetic Toxicology Testing | 169 |
RepeatedDose Toxicity Studies | 203 |
Neuro and Behavioral Toxicology Testing | 225 |
Reproductive Hazards | 301 |
Developmental Toxicology | 383 |
Assessment and Modeling of the Biological Hazards of Combustion Products | 411 |
Practical Statistical Analysis | 465 |
Placing and Monitoring Testing at External Facilities | 541 |
Hazard and Risk Assessment | 579 |
Toxicokinetic Studies in the Commercial Development of Agricultural and Industrial Chemical Products | 641 |
| 689 | |
Common terms and phrases
absorption activity acute toxicity additional aerosol analysis animal testing approach assay Behavioral Toxicology bioassay biological body weight carcinogenesis carcinogenicity cells chamber chromosomal combustion compounds concentration dermal determine developmental toxicity dose levels dose-response Drug effects endpoints evaluation experimental exposure factors female fertility function genetic guinea pig hazard Health human induction inhalation irritation laboratory lethal lymphoma male measured metabolism methods mg/kg 3 animals mice mouse mutagenicity mutation neurotoxicity observed OECD oocyte OPPTS oral organ parameters patch Pesticide pharmacokinetic potential procedure protocol rabbit rats raw data regulatory reproductive response risk assessment rodents sample screen sensitization skin species sperm spermatogenesis statistical Table techniques teratogenesis teratogenic Teratology test animals test article Test Guidelines test material test substance tion tissue toxicity studies toxicity testing Toxicol Toxicology tumor U.S. EPA variables vehicle vitro volume xenobiotic Zabol