Protein-carbohydrate Interactions: Deoxylactosides as Probes for the Binding Specificity of Beta-galactoside Binding LectinDepartment of Organic Chemistry 2, The Chemical Center, University of Lund, 1996 - Carbohydrates - 125 pages |
Contents
GLYCOCHEMISTRY IN PRACTICE | 22 |
nonreducing end of lactose | 29 |
RECOGNITION STUDIES | 55 |
3 other sections not shown
Common terms and phrases
13C NMR 1H NMR data 2-(Trimethylsilyl)ethyl according to procedure acid AcO OAC added Anal animal lectins anomeric anomeric effect antibodies aqueous benzyl binding constants Biol bromide BzIO Calcd carbohydrate CCH2Si Celite cells ceramide ceramide unit CH2CH2CO CHCl3 CHCSi Chem chromatographed SiO2 complex formation Compound crystal structure dABd dABq deoxygenation E-selectin EcorL enthalpy entropy epitope Et2O EtOAc/heptane Ferrier rearrangement Flash chromatography Galectin glucopyranoside glycoconjugates glycoside glycosphingolipid glycosyl hemiacetal hydride hydrogen bonds hydrogenolysis hydrophobic interactions isolated LacNAc lactose lactoside lectins Mass spectrum MeLacNAc MeOH methyl mixture was filtered mixture was stirred mmol molecules mono-deoxy monosaccharides NaHCO3 NMR data CD3OD NMR data CDCl3 OBzl OH OH oligosaccharide ortho-ester protective group protein R²=H reaction mixture receptor refluxing residue was chromatographed room temperature saturation Scheme silver silicate SiMe3 simulations solution stirred at room substrate sugar surface synthesis TMSEt toluene trichloroacetimidates yield