Safety Evaluation and Regulation of Chemicals 2: Impact of Regulations, Improvement of MethodsFreddy Homburger |
Contents
International Regulations | 11 |
The Approach to Safety Evaluation and Control of Chem | 19 |
Effectiveness of International Chemicals Man | 31 |
Copyright | |
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2nd Int acetaminophen acid activity agents animals assay Basel behavioral Behavioral toxicology benzo(a)pyrene biochemical cadmium Cambridge cancer carcinogenesis carcinogens carnitine cell culture cellular clofibrate compounds concentration Contemporary Worldview curve cytochrome P-450 cytosolic cytotoxicity dosage dose drug effects environment environmental enzyme epigenetic Evaluation and Regulation experimental experiments exposure fraction genotoxic GENPOP groups guidelines hamster hazards Health hepatic hepatocytes Homburger human incubation induction industrial inhalation isolated judgments Karger lauric acid LD test levels liver mechanisms medium metabolism metabolites microsomal nafenopin OECD palmitoyl-CoA oxidation peroxisome peroxisome proliferation potential primary cultures procedures protein synthesis rat hepatocytes rDNA reactive Regulation of Chemicals regulatory response risk assessment risk management Safety Evaluation Sample scientific specific studies substance TADV teratogenic teratology tissue toxicity Toxicol toxicology transformation trypan blue TSCA tumor vitro vivo µg/ml