The Metabolic Pathway Engineering Handbook: Tools and Applications, Volume 1Christina Smolke This second volume of the Metabolic Pathway Engineering Handbook delves into evolutionary tools and gene expression tools for metabolic pathway engineering. It covers applications of emerging technologies including recent research genome-wide technologies, DNA and phenotypic microarrays, and proteomics tools for experimentally determining flux thro |
Contents
1-1 | |
2-1 | |
Chapter 3 Engineering DNA and RNA Regulatory Regions through Random Mutagenesis and Screening | 3-1 |
Chapter 4 Evolving Pathways and Genomes for the Production of Natural and Novel Compounds | 4-1 |
Chapter 5 Models Predicting Optimized Strategies for Protein Evolution | 5-1 |
5-29 | |
Chapter 6 LowCopy Number Plasmids as Artificial Chromosomes | 6-1 |
Chapter 7 Chromosomal Engineering Strategies | 7-1 |
14-13 | |
Chapter 15 Systems Biology GenomeScale Models and Metabolic Engineering | 15-1 |
Chapter 16 CellFree Systems for Metabolic Engineering | 16-1 |
Chapter 17 In Silico Models for Metabolic Systems Engineering | 17-1 |
17-25 | |
Chapter 18 GCMS for Metabolic Flux Analysis | 18-1 |
Chapter 19 Tools for Measuring Intermediate and Product Formation | 19-1 |
Chapter 20 Use of AEXHPLCESIMS for 13CLabeling Based Metabolic Flux Analysis in Saccharomyces cerevisiae and Penicillium chrysogenum | 20-1 |
Chapter 8 Regulating Gene Expression through Engineered RNA Technologies | 8-1 |
Chapter 9 Tools Designed to Regulate Translational Efficiency | 9-1 |
Chapter 10 Metabolic Engineering of the Secretory Processing Pathway in Eukaryotes | 10-1 |
Chapter 11 Engineering Multifunctional Enzyme Systems for Optimized Metabolite Transfer between Sequential Conversion Steps | 11-1 |
Chapter 12 Practical Pathway EngineeringDemonstration in Integrated Tools | 12-1 |
12-15 | |
DNA Microarrays Phenotypic Microarrays and Proteomics | 13-1 |
Chapter 14 Monitoring and Measuring the Metabolome | 14-1 |
VE-1 | |
Chapter 21 Energy and Cofactor Issues in Fermentation and Oxyfunctionalization Processes | 21-1 |
An Emerging Technology | 22-1 |
Chapter 23 Applications of Metabolic Engineering for Natural Drug Discovery | 23-1 |
Chapter 24 Metabolic Engineering for Alternative Fuels | 24-1 |
Back cover | 24-29 |
Other editions - View all
The Metabolic Pathway Engineering Handbook: Tools and Applications Christina Smolke No preview available - 2017 |
The Metabolic Pathway Engineering Handbook, Two Volume Set Christina Smolke No preview available - 2009 |
Common terms and phrases
Acad activity amino acid aptamer artemisinin bacterial binding Biochem Bioeng Biol biological biosynthesis Biotechnol Biotechnology carbon carotenoid catalytic cell cell-free cellular Chem chemical chromosome cloning codon cofactor complex deletion developed directed evolution DNA shuffling domain efficient encoding energy enzymes epothilone Escherichia coli ethanol fermentation Figure flux analysis functional gene expression genetic genome glucose growth heterologous host improved increase insertion interactions intracellular isotopomer ligand metabolic engineering metabolic flux metabolic network metabolic pathways metabolites metabolome method microarray microbial Microbiol molecular molecules mRNA mutagenesis mutations NADH Natl Nucleic Acids Res optimization overexpression phenotype plasmid precursor Proc production promoter protein proteome random reaction recombinant regulation regulatory ribosome riboswitches ribozyme Saccharomyces cerevisiae screening selection sequence shuffling silico specific spectrometry strain strategies structure substrate synthase synthesis synthetic target techniques technologies tion transcription vectors vitro vivo xylose yeast yield