Toxins and Targets: Effects of Natural and Synthetic Poisons on Living Cells and Fragile Ecosystems

Front Cover
Dianne Watters
Taylor & Francis, 1992 - Medical - 199 pages

First Published in 1992. The last decade of the twentieth century has seen an unprecedented advocacy for the preservation of a safe environment, and the prevention of ill-health from toxic chemicals. Human activity, however, is responsible for introducing new toxins into the environment. In order to control competitors for human food sources, an armament of pesticides has been assembled and their widespread and largely uncontrolled application has been permitted. It is only when the health of the population begins to suffer from the effects of these chemicals that the efficacy of their use is questioned. Decision-makers whose roles involve the promotion and control of the environment must look to lessons that can be learnt from biosystems that include animals other than man.

Toxins and Targets details the way in which organisms from diverse habitats in the plant and animal kingdoms have adapted to handle toxins safely. Part I, on the aquatic environment, highlights the means by which marine organisms have adapted their toxins to be effective in a world of high aqueous solubility and infinite dilution. Part II deals with venomous terrestrial organisms and the mechanisms by which they damage animal cells, and Part III considers the way in which human society attempts to investigate toxicity and to control both synthetic and naturally occurring poisons. The development of a safe environ-ment depends on increased knowledge and novel approaches to solving escalating problems. This book is a step towards this end.

 

Contents

Chapter
1
Chapter 3
19
Chapter 4
29
Chapter 5
35
Chapter 6
49
Chapter 7
55
Immunotherapy for CancerToxinAntibody
65
A Tick Toxin
75
The Exotoxin of Melloidosis a Disease
109
Two Naturally Occurring Toxins Causing
119
A Jellyfish Toxin
131
Snake VenomHaemostatic Components
139
A Toxic Protein from the AIDS Virus
149
Toxicity Testing
157
The Effects of Chloropropanes
163
Biomonitoring of DNADamaging Toxins
171

A Cycad Neurotoxin
81
Ciguatera Poisoning
87
FunnelWeb Spider Toxins
97
Tetanus Toxin
103
Organochlorines Pollutants and Human
177
Ecotoxicology
185
Index
195
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About the author (1992)

Dianne Watters, Martin Lavin both Queensland Cancer Fund Research Unit, Queensland Institute of Medical Research, Brisbane, Australia. David Maguire Division of Defence and Technology, Griffith University, Brisbane, Australia. John Pearn Faculty of Medicine and Department of Child Health, University of Queensland, Royal Children's Hospital Brisbane, Australia.

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