Clinical in Vitro Fertilization
Carl Wood, Alan Trounson
Springer-Verlag, 1989 - Fertilization in vitro, Human - 166 pages
In vitro fertilization has resulted in an estimated 4000-5000 births in the world. The procedure has been accepted in Europe, America and Australia and several hundred IVF clinics are operating successfully. The newer procedures of GIFf, embryo freezing and donor oocyte IVF have become established and are dealt with in several chapters. GIFf has become the procedure of choice for patients with infertility of unknown origin. Oocyte freezing represents an important new technology which is being developed. The routine IVF procedure has improved slightly; variation in results can be reduced by quality control of laboratory and clinical techniques. Male factor infertility has been dealt with by IVF in mild and moderate cases, but newer techniques will be required to deal with severe problems in the male. Most countries have accepted that the straightforward IVF pro cedure is ethical. Limitations concerning the use of donor oocytes and embryo experimentation exist in some religions and countries; legal control of the new reproductive technologies ranges from the passage of statutes to no control at all. Many countries are still considering the need for legislative control. The text endeavours to indicate new areas of importance and to guide those organizing services as to how to introduce newer technolo gies.
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1,2-propanediol abnormal Asch assessment Australia births blastocysts cell chromosomal cleavage stage clinical couples cryopreservation cryoprotectant culture medium cumulus DMSO donation ectopic pregnancy eggs embryo transfer Fert Embryo Transfer Fertil Steril fertilization and embryo fertilization rate follicle aspiration freezing gamete intrafallopian transfer gametes GIFT glycerol gonadotrophin hormone human embryos human in vitro human oocytes human spermatozoa increase infertility inhibin insemination IVF pregnancies IVF programme Kovacs laboratory laparoscopy Leeton liquid nitrogen male factor infertility menstrual cycle method Monash motile sperm mouse embryos multiple pregnancy National Perinatal Statistics normal oestradiol oocyte collection oocyte retrieval outcome ovarian ovaries ovulation patients Perinatal Statistics Unit phosphate buffered saline pregnancy rate procedure progesterone pronuclear Reprod Fertil semen sample serum slow cooling solution sperm concentration spermatozoa stimulation studies success rate sucrose survival technique temperature thawed treatment cycle Trounson tubal ultrasound vaginal viability vitrification Vitro Fertil Embryo vitro fertilization women Yovich zona pellucida