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abnormal Acad acid agents albinos Anat anencephaly animals anomalies antibody antigens associated Biol birth blood cataract cause cent chemical chick embryo chromatin cleft palate clinical congenital defects congenital malformations cytoplasm death developmental differentiation disease early ectodermal embryo environment environmental enzyme etiology evidence example experimental experiments factors female fetal fetus fetuses formation frequency ganglia gene genetic genital malformations genotype gestation gland gonadal gonadal dysgenesis growth hormones human incidence induced infants infection influence interaction investigation karyotype male mammals maternal age maternal effects mations mechanisms ment metabolic mice mongolism mother mouse mutation nerve cells normal nuclear nuclei observed occur ovum oxygen patent ductus arteriosus Pelger phenotype pigment placenta population pregnancy problem Proc produced Professor protein rabbit rubella salivary sex chromatin specific stage stillbirths strain syndrome teratogenesis teratogenic tion tissue translocation trophoblast Turner's syndrome uterine uterus virus viruses Zool