Cellular and Molecular ImmunologyThe meticulously revised and updated New Edition of this highly acclaimed text continues to provide a concise and straightforward approach to the subject. It focuses on the experimental observations that underlie the science of immunology at the molecular, cellular, and whole organism level-and explores the conclusions that can be drawn from those observations.
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activation adaptive immune adhesion anti antibodies antigen receptors APCs associated binding blood bone marrow called cause CD4+ T cells cell activation cellular chain Chapter class II MHC complement complex components contain CTLs cytokines cytoplasmic dendritic cells described differentiation discussed disease domains effector effects encoding endothelial enzymes expression factor Figure function gene graft heavy helper T cells host human IFN-y immune responses immune system important increased individual induce infection inhibit initiated innate immunity interactions intracellular involved kill kinase leads leukocytes ligand lymphocytes lymphoid macrophages major mast cells maturation mechanisms mediated membrane MHC molecules mice microbes mouse naive naive T cells NK cells nodes normal organs pathway patients peptides phagocytes present produced proliferation promote reactions recognition recognize regions rejection result role secreted selection sequences signals specific stimulate structure surface tion tissues tolerance transcription tumor viral virus