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A SIMULATION MODEL FOR IN VITRO
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A.Yu analysis Biol biological branching processes cell biology cell culture cell cycle cell death cell kinetics cell population cell proliferation cell survival cell system cells irradiated characteristics cloning complex computer simulation cycle phase damage repair described differentiation distribution dynamics epithelium equation estimator experimental data exponential factors Figure fractionated irradiation function G2 phase GPSS interval investigation ionizing radiation irradiated cells irradiation dose labelled mitoses lethal radiation damage levels of damage mammalian cells mathematical model MC phase methods mitotic cycle number of cells obtained phase duration plateau phase PLDR potentially lethal damage problems proliferating cells q-index radiation effect radioresistance radiosensitivity random realizations repair efficiency Repair of potentially repair processes resting cells Russian simulation experiments simulation languages simulation model SLDR stem cells stochastic stochastic processes subpopulations survival of cells synchronized temporal parameters theory tion tissue total number transition tumour tumour cells variance vitro Yakovlev