Basic and systemic mechanisms of anesthesia

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Elsevier, 2005 - Medical - 342 pages
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This book is constituted of the presentations (symposium, workshop and posters) given at the Seventh International Conference on Molecular and Basic Mechanisms of Anesthesia, held in Nara, Japan during February 2005. During this international event leading researchers presented the latest findings on the mechanisms underlying states of anesthesia. Topics covered included the latest developments in the physico-chemical actions of anesthetics on the membrane, to the molecular identifications such as their receptor-mediated actions. Furthermore, new research was presented on developments in the molecular identification of general anesthetic targets at the receptor level and the functional roles of their molecular targets, revealed by their integration of the in vivo system using genetic engineering techniques. An essential text for all researchers wanting a concise and authoritative overview of current research in the field of mechanisms of anesthesia, this book is a timely update for everyone involved in anesthetic drug development.

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Contents

Molecular mechanisms of general anesthetic action
3
Mechanisms and sites
21
Anesthetic sensitivity is reduced in hippocampal pyramidal neurons from GABAA
38
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