Retroviruses: Strategies of ReplicationRonald Swanstrom, Peter K. Vogt This book gives a synthesis of current knowledge on ret- rovirology. Each chapter deals with a different step in the virus life cycle, detailing the molecular aspects of virus replication. The comparison of different retroviruses exemplifies variations. Specific topics include the evolution of retrovirus genomes, integration of the provirus, viral DNA transcriptional and translational control of viral gene expression, processing of viral proteins, and packaging of virion RNA. Data on HIV and HTLV-1 are covered as well as research on animal retrovirus sys- tems. |
Contents
R F DOOLITTLE D F FENG M A MCCLURE | 1 |
Integration of Retroviral DNA | 19 |
The Structure and Function of Retroviral | 49 |
Copyright | |
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Acad Sci USA activity amino acid analysis antibodies antigenic avian binding cell lines cellular cleavage cloned codon Coffin Cold Spring Harbor coli deletion disease domain ecotropic efficient encapsidation encoded endogenous enhancer env gene product frameshifting gag gene genetic genome genomic RNA glycoprotein helper virus host range HTLV-I human immunodeficiency virus human T-cell leukemia infected cells integration isolated LINIAL long terminal repeat mammary tumor virus mice MMTV molecular Moloney murine leukemia mouse mammary tumor mRNA MuLV murine leukemia virus mutations Natl Acad Sci nucleotide sequence oncogene Oroszlan packaging cell particles peptide pol gene polyprotein precursor Proc Natl Acad protease proteinase provirus reading frame receptor recombinant region replication retrotransposons retroviral retroviruses reverse transcriptase ribosomal frameshifting Rous sarcoma virus specific splicing stem-loop structure subgroup suppression synthesis T-cell leukemia virus target DNA transcription translation tRNA Varmus vector viral DNA virions Virol 62 Virology visna vitro Weiss