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activity aerobic metabolism Alli.m Oep Andersen and Gravenstein anesthesia anesthetic agents anesthetic concentrations anesthetic effect animal tissue antimitotic effect antimitotic poison ascorbic acid ATP-ase barbiturates block c-mitosis c-mitotic cardiac glycosides cause c-mitosis cell division cellular chick embryo chloral hydrate chromosomes clinical CNS depressants co-enzyme colchicine compounds conﬁrm congenital abnormalities contractile contraction and elongation decreased deﬁciency dehydrogenase DNA synthesis e\oe effect of anesthetic EFFECT OF CNS effect of colchicine Eigisti and Dustin electron transporting energy enzymatic enzymes ethyl ether ﬁbroblasts ﬁndings ﬁrst give rise glucose glycolysis in'c increase in substance instance interfere Lettré lipoid solubility metaphase metaphasic arrest mice mitochondria mitochondrial electron mitosis mitotic apparatus mitotic index mitotic spindle Molar conc morphologic muscle narcotics nitrous oxide oxidase oxygen Phenyl urethane phosphagen prophase respiration result shown signiﬁcant similar speciﬁc spindle poison Staudinger studies teratogenic thalidomide theory tion tumor urethane vitamin vitro vivo Warkany