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ACCP acute adverse events airway alleles American College analysis anaphylaxis apnea assessment associated asthma baseline biomarkers bosentan bronchoscopy BROVANA budesonide cardiac cardiovascular cells chemokines Chest Physicians chronic obstructive pulmonary Clin clinical College of Chest COPD COPD patients corticosteroids CPAP criteria Critical Care Medicine CXCL9 CXCR3 decrease diagnosis drugs e-mail effect episodes evaluated exacerbations FCCP Feno fibrosis fluid formoterol Health Healthcare hemoptysis hospital hypertension increased infection inflammation influenza leptin levels linezolid liver lung cancer lung disease lung function measured mechanical ventilation neutrophils obstructive pulmonary disease oral OSAS outcome P-selectin patients treated placebo plasma pneumonia potential predicted pulmonary arterial Pulmonary/Critical Pulmonologist ratio reported Respir Crit respiratory response risk salmeterol score serum significant sildenafil simulation Sleep Medicine smokers spirometry sputum SYMBICORT symptoms systemic Table therapy Thoracic tion TRACLEER treatment trials TYGACIL vaccination values variables Xoiair ZYVOX