Narcissus and Daffodil: The Genus Narcissus (Google eBook)

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Gordon R Hanks
CRC Press, Sep 2, 2003 - Science - 452 pages
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Narcissus and Daffodil is the first book to provide a complete overview of the genus Narcissus. Prized for centuries in western Europe as an ornamental plant, it has recently attracted attention as a source of potentially valuable pharmaceuticals. In eastern European countries, however, Narcissus and other Amaryllidaceae have been valued as a source of galanthamine for several decades.
Presenting original research material and information not accessible outside eastern Europe, Narcissus and Daffodil contains over 1,700 references, making it an invaluable text for graduates and researchers both in academia and industry. It will be of particular importance for people working in the fields of horticulture, agriculture, medicine, pharmacology and perfume chemistry and drug manufacture.
  

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Contents

1 The biology of Narcissus
1
2 The folklore of Narcissus
19
3 Classification of the genus Narcissus
30
4 Commercial production of Narcissus
53
5 Economics of Narcissus bulb production
131
6 Alkaloids of Narcissus
141
7 Production of galanthamine
215
8 Narcissus and other Amaryllidaceae
242
11 Extraction and quantitative analysis
286
12 Synthesis of galanthamine and
304
clinical trials
355
15 Screening of Amaryllidaceae
369
16 Narcissus lectins
380
17 Narcissus in perfumery
392
18 Harmful effects due to Narcissus
399
19 Review of pharmaceutical patents
408

9 Studies on galanthamine extraction
256
10 Galanthamine production from
273

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Page viii - PREFACE TO THE SERIES There is increasing interest in industry, academia and the health sciences in medicinal and aromatic plants. In passing from plant production to the eventual product used by the public, many sciences are involved. This series brings together information which is currently scattered through an ever increasing number of journals. Each volume gives an in-depth look at one plant genus, about which an area specialist has assembled information ranging from the production of the plant...
Page ix - Asia. A similar situation exists in Africa and South America. Thus, a very high percentage of the world's population relies on medicinal and aromatic plants for their medicine. Western medicine is also responding. Already in Germany all medical practitioners have to pass an examination in phytotherapy before being allowed to practise.
Page viii - DNA is giving rise to controversy in the case of some enduses of the plant material. Some suppliers of plant raw material are now able to certify that they are supplying organically- farmed medicinal plants, herbs and spices. The Economic Union directive (CVO/EU No 2092/91) details the specifications for the obligatory quality controls to be carried out at all stages of production and processing of organic products.
Page ix - Medicine and this office in 1994 assisted the filing of several Investigational New Drug (IND) applications, required for clinical trials of some Chinese herbal preparations. The significance of these applications was that each Chinese preparation involved several plants and yet was handled as a single IND. A demonstration of the contribution to efficacy, of each ingredient of each plant, was not required. This was a major step forward towards more sensible regulations in regard to phytomedicines....
Page ix - The high costs of such ventures and the endless competition from me too compounds from rival companies often discourage the attempt. Independent phytomedicine companies have been very strong in Germany. However, by the end of 1995, eleven (almost all) had been acquired by the multinational pharmaceutical firms, acknowledging the lay public's growing demand for phytomedicines in the Western World. The business of dietary supplements in the Western World has expanded from the Health Store to the pharmacy....
Page iii - ... of industrial importance. Edited by Dr Roland Hardman Volume 1 Valerian, edited by Peter J. Houghton Volume 2 Perilla, edited by He-ci Yu, Kenichi Kosuna and Megumi Haga Volume 3 Poppy, edited by Jeno Bernath Volume 4 Cannabis, edited by David T.
Page viii - Natural products do not mean safe products and account of this has to be taken by the above industries, which are subject to regulation. For example, a number of plants which are approved for use in medicine must not be used in cosmetic products. The assessment of safe to use starts with the harvested plant material which has to comply with an official monograph. This may require absence of, or prescribed limits of, radioactive material, heavy metals, aflatoxin, pesticide residue, as well as the...
Page ix - Alternative medicine includes plant based products. Appropriate measures to ensure the quality, safety and efficacy of these either already exist or are being answered by greater legislative control by such bodies as the Food and Drug Administration of the USA and the recently created European Agency for the Evaluation of Medicinal Products, based in London. In the USA, the Dietary Supplement and Health Education Act of 1994 recognised the class of phytotherapeutic agents derived from medicinal and...
Page ix - Cinchona and Artemisia. The methods of detection of pharmacological activity have become increasingly reliable and specific, frequently involving enzymes in bioassays and avoiding the use of laboratory animals. By using...

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