All-fiber Endoscopic Optical Imaging Devices

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ProQuest, 2009 - 139 pages
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Optical coherence tomography (OCT) is an emerging imaging modality that is capable of providing noninvasive, subsurface optical imaging of biological tissues with micron-scale resolution. The operation of an OCT system is based on the principle of interferometry, which uses the low coherence interference between a reference and a signal beam derived from a broadband optical source. It can be used to generate slice images of three-dimensional objects at a resolution level much greater than that currently available using MRI, CT scan, or ultrasound scans. One of the goals of this dissertation is to design and test a compact all-fiber Fourier Domain Optical Coherence Tomography (FD-OCT) system based on a common-path interferometer configuration, to develop the software algorithms necessary to acquire cross-sectional biological tissue images at high refresh rates, to provide various scanning approaches for the fiber optic probes and to optimize and analyze the system sensitivity for various specific applications.
  

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Contents

Basic Fiber Optics
7
Optical Coherence Tomography
34
OCT System and Results
56
Confocal microscopy
85
Endoscopic Fiber Confocal Microscopy with a GRIN Lens
104
Conclusion
116
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