Signaling mechanisms and gene expression in the ovary
The latest developments in ovarian physiology are presented in this book. Based on a proceedings from the Ovarian Workshop developed by Dr. A. Rees Midgley and held biennially since 1976, the contributions will be of interest to all those concerned with the ovarian field. The book focuses on the expression of hormonally and non-hormonally controlled genes involved in the functional and morphological differentiation of cells forming the ovary. It also examines the signaling mechanisms by which endogenous and exogenous hormones and cytokines affect ovarian differentiation and steroidogenesis.
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Structural Insights Learned from
Hormonal Regulation of Gonadotropin Gene Expression
Inositol Lipid Metabolism and Calcium Signaling in
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3P-HSD mRNA action activity adenylate cyclase androgen angiotensin antibody aromatase assay binding Biochem Biol Chem Biol Reprod blot bovine luteal cells C-kinase calcium cAMP cDNA cellular cholesterol concentrations corpora lutea corpus luteum cultured differentiation effect Endocrinol Endocrinology endogenous enzyme estradiol estrogen expression Figure follicular fluid forskolin function gene GnRH gonadotropin granulosa cells growth factor human hybridization IGF-I increase incubated inhibin inhibition inhibitor inositol intracellular large cells LH/CG receptor luteal cells luteal phase luteinizing hormone luteolysis macrophages maturation medium membrane mRNA ng/mL oocytes ovary ovulation pathway PGF2a phorbol ester phosphorylation pregnancy preovulatory follicles presence progesterone progesterone production progesterone secretion progestin prostaglandin protein kinase pseudopregnancy rat granulosa cells rat luteal rat ovary regulation relaxin response role sequence serum specific steroid steroidogenesis steroidogenic stimulated studies synthesis theca interna tion tissue transcription treatment Tumor necrosis vitro vivo