Pharmacology: Principles and Practice (Google eBook)

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Academic Press, Jun 19, 2009 - Science - 608 pages
2 Reviews
This unique and much needed textbook meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker, et al. to help train new drug researchers.

The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, Pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process.

*Uses individual drugs to explain molecular actions
*Full color art program explains molecular and chemical concepts graphically
*Logical structure reflecting the current state of pharmacology and translational research
*Covers such intricacies as drug resistance and cell death
*Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool
  

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Its really agreat book
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.
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Dr. Mubi
USA
 

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In times when there are a plethora of pharmacology books, this book is unique in its clear presentation of a potentially complex subject matter. The book is clearly a modern pharmacology text.
Oscar A. Linares, MD

Contents

History of PharmacologyFrom Antiquity to the Twentieth Century
1
Dosage Forms and Their Routes of Administration
9
Membranes and Drug Action
31
LigandReceptor Binding and Tissue Response
63
Hormesis and Pharmacology
75
Signal Transduction and Second Messengers
103
Drug Distribution
113
Drug Metabolism
131
Adverse Drug Reactions
327
Risk Assessment
353
Drug Resistance
371
Ion Channels
387
Targeting the Cell Cycle to Kill Cancer Cells
429
Programmed Cell Death
455
Drug Discovery
475
Genomics and Proteomics in Drug Design and Discovery
561

Drug Excretion
175
Pharmacokinetic Modeling
201
Bioanalytical Tools for Drug Analysis
279
DrugDrug Interactions with an Emphasis on Drug Metabolism and Transport
303
The Future of Pharmacology
575
Index
581
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