Molecular recognition mechanisms
VCH Publishers, 1991 - Medical - 285 pages
'Molecular Recognition Mechanisms' is a modern approach to the study of the molecular basis of interactions between chemical and biological systems. Compiled by some of France's most eminent specialists in the field, this book adopts a multidisciplinary point of view in describing and explaining the complex subject of biological macromolecules (DNA, antibodies, receptors, enzymes, cell membranes) and their interaction with smaller molecules, both natural and synthetic.
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PhysicoChemical Aspects of Molecular Recognition
Kinetic aspects of recognition processes
2 Membrane Transport Daniel SCHERMAN
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ACE inhibitors acid proteases acid sequence active affinity agonist allows amino acids analogues angiotensin angiotensinogen antigen arterial pressure atoms bacteria bases benzodiazepine benzodiazepine receptors binding sites biological bond calculations captopril carrier catalytic chemical chromaffin granule cleavage complementary complex compound concentration conformation corresponding covalent derivatives diazepam drugs effect elastase endocytosis enzymatic enzyme equilibrium example Figure fluorescence function gene expression GlcNAc glycoconjugates glycoproteins gradient helix hepatocytes hydrophobic hypertension immune immunoglobulins increase inhibition interaction intercalating agent kinetics labelled large number lectins ligand lymphocytes lysosomes macrophages membrane lectins messenger RNA method modified molecular molecules monoamine monoclonal antibodies Monsigny mutagenesis neoglycoproteins nucleic acid obtained oligonucleotide oligosaccharides pepsin pepstatin peptide perindopril pharmacological plasma membrane polypeptide chain possible properties protein proton reaction receptor recognition renin renin inhibitors repressor role specific structure substrate synthesis target technique therapeutic transport tumor cells uptake vesicles vitro vivo