Genetic Disorders Among Arab Populations
Ahmad S. Teebi, Talaat I. Farag
Oxford University Press, 1997 - Medical - 499 pages
Few regions of the world have a more varied physiography or a richer ethnic, religious, social, and cultural mix than the Arab world. As a consequence, Arabs are genetically diverse despite their linguistic and religious cohesion. High but variable rates of inbreeding prevail in all Arab countries with numerous examples of isolates among them. These include some Bedouin groups, Nubians, Druze, Jews, and others. Arab populations have high frequencies of autosomal recessive disorders, homozygosity of autosomal dominant and X-linked traits, and a wealth of new syndromes and variants, the majority of which are autosomal recessive. Genetic disorders that cause major health problems include hemoglobinopathies, neurogenetic disorders, inherited metabolic diseases, and inborn error of morphogenesis. Because of their characteristically high prevalence, some of these disorders are considered markers for Arab populations.
This book presents the unique profile of genetic disorders and variants in Arabs. In addition, it describes their unusual demographic pattern including fertility rates and other population dimensions, family structure, magnitude and effects of consanguineous marriages and indicators of health and disease. Genetic counseling and the distinctive cultural and religious attitudes towards various genetic issues are also presented. Disorders that have increased tribal occurrences or are limited to large kindreds, as well as small geographic or religious isolates, are highlighted to facilitate their recognition, study, and management.
What people are saying - Write a review
We haven't found any reviews in the usual places.
Population Dimensions in the Arab World
The Arab World
Endogamy in the Arab World
Hemoglobinopathies in Arab Countries
Familial Paroxysmal Polyserositis Familial Mediterranean Fever
Neuromuscular Disorders Among Arabs
Genetic Disorders in Arab Countries and Geographic Regions
Genetic Diseases Among Jordanians and Palestinians
Genetic Disorders in Sudan
Genetic Disorders in the United Arab Emirates
Genetic Studies in Isolated and SemiIsolated Communities
The Egyptian Nubian People of Kom Ombo
Genetic Disorders Among Jews from Arab Countries
Cultural and Religious Attitudes Towards Genetic Issues
Psychosocial and Medical Aspects of Genetic Counseling Among
Genetic Diseases in Lebanon
abnormalities Al-Awadi Algeria allele anemia anomalies Arab countries Arab populations Arab world Armenian associated autosomal dominant autosomal recessive Bahrain Bayoumi Bedouin Beirut child chromosome Clin Genet clinical communities congenital consanguineous consanguineous marriages cousin Cystic fibrosis defects dehydrogenase diagnosed drome Duchenne dysplasia dystrophin Egypt Egyptian El-Hazmi MAF familial Mediterranean fever Farag Faragetal frequency G6PD deficiency gene genetic diseases genetic disorders groups Hamamy Hamida haplotype Hashem Hassan hemoglobin hemoglobinopathies Hum Genet inbred inbreeding incidence inheritance Iraq Iraqi Israel Jewish Jews Jordan Jordanians Kaloustian VM Khlat Kuwait Lebanese Lebanon linkage males mental retardation molecular Morocco muscle muscular dystrophy Muslims mutation Naguib Nubian Palestinians parents patients Pediatr phenotype phenylketonuria polymorphic prevalence protein region reported Salih Saudi Arabia SCARMD Schwartz-Jampel syndrome siblings sibs sickle cell disease Sudan Sudanese syndrome Teebi Temtamy thalassemia tion Tunisia variant Warsy Yemen Zlotogora