Drugs for Rheumatic DiseaseHarold E. Paulus, Daniel E. Furst, Sydney H. Dromgoole |
Contents
Concepts and Targets for Drug Treatment of Chronic | 1 |
Antimalarial Drugs | 5 |
Basic Concepts in Pharmacokinetics | 9 |
Copyright | |
23 other sections not shown
Common terms and phrases
acid action activity acute administration adverse agents allopurinol anti-inflammatory appears Arthritis Rheum aspirin associated binding blood cause cells changes chloroquine chronic clearance Clin Pharmacol clinical colchicine compared comparison complex compounds concentrations controlled coworkers D-penicillamine daily decreased differences disease dosage dose double-blind drug effects efficacy elimination et al excretion fenoprofen fluid function given gold gout half-life human ibuprofen immune improvement increased indomethacin induced inflammatory inhibition interaction Intern ketoprofen less levels lymphocytes mechanism metabolism metabolites mg/day naproxen normal NSAIDs occur oral patients percent Pharmacokinetics phenylbutazone placebo plasma platelet prevent probenecid produce prostaglandin protein rats reactions renal reported response rheu rheumatic rheumatoid arthritis Rheumatol salicylate serum shown side effects significant steroid subjects suggested sulindac synovial fluid synthesis systemic Ther therapy tients tion tissue tolmetin toxicity treated treatment trial urate uric acid urine vitro weeks