New Advances in Thoracic Oncology: From Scientific Evidence to Optimal Management
This publication brings together selected experts whose daily work is dedicated to both research and clinical activity in the field of primary lung cancer. A special effort has been made to select papers which do not simply repeat universally recognized evidence, but which explore either new orientations, or marginal and debatable issues. Part I exposes problems related to early diagnosis and staging, and discusses prognostic factors. We know that lung cancer screening is an issue of ongoing debate in public health, as economists question its cost-efficiency. Detection of indeterminate nodules might even worsen the expenditures. Tumor markers, as evidenced in peripheral blood samples, may contribute substantially to diagnosis and prognosis of lung cancer. Positive tissue diagnosis of primary tumor and draining lymph nodes is of increasing importance because of the introduction of multi-modality treatments, and hence requires invasive staging methods. Part II discusses the different options of surgical treatment. There is no debate that complete surgical resection is the only way to cure a patient suffering from lung cancer. The role of lymph node dissection has considerably increased over the last decade. There is now increasing evidence that a thorough lymph node dissection does not only improve the reliability of staging, but also increases survival.
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The Role of Serum Tumor Markers in Lung Cancer
Restaging after Induction Therapy for Nonsmall Cell Lung Cancer
Lymphatic Spread and Lymph Node Involvement of Nonsmall Cell Lung
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anastomosis anatomical Ann Thorac Surg biopsy bleeding bronchial artery bronchial fistula bronchial stump bronchoplastic bronchoscopy bronchus Cardiothorac Surg cell carcinoma cell lung cancer chest wall Clin clinical comorbidity complete resection complications computed tomography contralateral Cyfra detection diagnosis disseminated tumor cells embolization Evidence to Optimal fistula hemoptysis induction chemotherapy induction therapy invaded invasion lesions lobectomy long-term lymph node dissection lymphadenectomy malignant SVCS markers Massard massive hemoptysis mediastinal lymph nodes mediastinoscopy mediastinum metastases micrometastases morbidity mortality muscle N2 disease needle aspiration neoadjuvant therapy neoplasms nodal non-small cell lung NSCLC Oncol oncological operation Optimal Management pathologic performed pleural pneumonectomy postoperative preoperative primary lung cancer procedure PTFE graft pulmonary artery radiotherapy reconstruction recurrence reported resection restaging risk screening serum sleeve resection small cell lung sternotomy subclavian superior vena cava surgical resection surgical treatment suture techniques Thorac Cardiovasc Surg Thoracic Surgery thoracoscopy thoracotomy thrombosis tomography upper lobe vein venous vessels