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animal Appelbaum and Roth assessment authenticity Belmont Report best interest biological biomedical brain Brother Fox chapter choice clinical clinicians coma conflict consent to treatment cooperation court criteria culture Darwin decision deliberation determine disability discussion disorders doctrine DSM-III effects electroconvulsive therapy ethical issues ethical problems evaluation evolutionary example function gametes genes genetic genotypes Hastings Center Rep human incompetent individual informed consent involved kin selection Lidz Lumsden and Wilson major histocompatibility complex mechanisms medicine Meisel mental Miller moral nature neurological notion outcomes particular paternalism patient's refusal person physician possible principles prognosis psychiatric diagnoses psychiatric patients psychoactive drugs question Quinlan rational reciprocal altruism recovery refuse treatment relevant requires respirator result risk Saikewicz selection sense of autonomy social behavior sociobiology specific standard of competency Storar substituted judgment Szasz tardive dyskinesia tests of competency theory treatment refusals understanding values W. D. Hamilton York