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Acad Sci USA activity AIDS Res Hum AIDS Vaccine amino acid analysis anti antigen assay binding cats CD4+ CD8+ cell lines cellular clinical clone complement culture cytokines cytotoxic data not shown detected disease domain donor DRVs effect envelope epitopes expression gene genetic genome glycoprotein HIV infection HTLV HTLV-I human immunodeficiency virus immune response immunodeficiency virus type Immunol incubated induced inhibition isolates lane lymphocytes macaques macrophages Mary Ann Liebert mice molecular molecules monoclonal antibodies monocytes mutations Natl Acad Sci Nature London NF-kB nucleotide observed patients PBMCs peptide peripheral blood plasma plasmid Proc Natl Acad production protein proviral recombinant region replication Res Hum Retroviruses Research Rev protein samples sequence sera serum simian simian immunodeficiency virus strains subtype supernatant T-cell target tested tion titers transfected trials V3 loop vector viral Virol viruses vitro vivo