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abnormal aging process alterations asaqq biological body bone brain calcification calciphylaxis Casarett cells cellular chromosome aberrations clones collagen Conference Presentation DR connective tissue correlation curve damage death decrease degradative change disease doses of radiation effects of irradiation effects of radiation embryo entropy experimental exposure factors following irradiation function genetic glomerulus Grahn ground substance growth increase induced inventory involved ionizing radiation irreparable late effects late irradiation effects lesions leukemia lipid longevity loss mammalian mammals MANIFESTATIONS OF LATE mechanisms membrane messenger RNA metabolism mice molecular molecule mucopolysaccharides normal occur organism parenchymal percent physiological Poisson distribution population Position Statement Preconference Statement problem produce progeria ptre q.aqq qaqq qq.pi question radiation injury relation result ROTHSTEIN rotifer Sacher SELYE senescence shortening SINEX somatic mutation span species Storer studies tion tumors Upton vascular vasculature