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activity addn administration agonist amino acid anal animals antagonist antibody assay assocd binding Biochem Biol blood brain Ca2+ catecholamine cDNA cell lines Chem chromosome Clin cloned coli Coll compds concn contg culture decreased detd detected dopamine dose drugs effects encoding enhanced enzyme Escherichia coli estradiol ethanol examd expression expts function gene Genet genomic growth factor hormone human hybridization IGF-I increased induced inhibition inhibitor injection Inst insulin interaction intracellular isolated Japan levels lipid liver membrane metab metabolites mg/kg mice mouse mRNA mutations Natl neurons nucleotide obsd peptide Pharm Pharmacol Physiol plasma plasmid potential prodn progesterone prolactin promoter protein rats receptor redn refs region regulation release resp response secretion sequence serotonin serum soln somatostatin Southern blot specific stimulation structure studied synthesis tissue toxicity Toxicol transcription treatment tumor Univ uptake virus vitro vivo