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addicts adoles adolescent drug abusers adults agencies alcohol amphetamines antismoking programs approach arrests barbiturates behavior cigarette smoking clients coca cocaine Colombia consumption cost crop develop dose drug education drug market drug treatment drug users drug-related effects efforts estimates evaluation evidence experimental factors family therapy federal grams hallucinogens heroin high school seniors high-level dealers Hilton Foundation illicit drugs important incarcerations increase Institute on Drug interdiction intervention investigations Jessor Kandel law enforcement less marijuana marijuana and cocaine ment methaqualone million Narcotics National Institute NIDA NNICC onset opiate opium outcome patterns peer percent physical dependence pressure prevention programs prison problem produce psychic psychoactive drugs rates reduce regular reported retail price retail value risks seizures social specific stimulant strategies studies substances suggest survey Table tion tranquilizers treatment programs U.S. Government U.S. Senate young youth