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UPTAKE AND TRANSPORT OF FOSINOPRIL IN CELL CULTURE
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ACE inhibitors amino acids apical and basal apical and basolateral apical membrane barrier basolateral membrane beta-lactam antibiotics Biochem Biochim Biophys Acta brain Brandsch brush border brush border membrane Caco-2 and SKPT Caco-2 cells cell culture cell line cell monolayers choroid plexus epithelial cloning corrected for nonsaturable Daniel H data from Table data were corrected dipeptide Dixon analysis drug efflux enalapril epithelium expressed as mean fosinopril fosinopril and zofenopril Fosinopril Uptake functional Ganapathy GlySar uptake Hediger high-affinity incubation intracellular accumulation Inui kidney kinetics of GlySar Leibach F H mannitol molecular monolayers mRNA nonsaturable uptake oligopeptide oligopeptide transporter oocytes organic anion transporting PEPT1 and PEPT2 peptide transporter PEPT2 Physiol plexus epithelial cells protein proton-coupled quinapril rabbit renal rat choroid plexus rat PEPT1 renal BBMV renal peptide transporters Sigma Chemical SKPT cells small intestine studies substrate Terada tissue transepithelial transport transport system transporter PEPT1 Trial 2 Trial uptake buffer uptake of GlySar zofenopril