Genomes 3 (Google eBook)

Front Cover
Garland Science, 2007 - Science - 713 pages
4 Reviews

Covering molecular genetics from the basics through to genome expression and molecular phylogenetics, Genomes 3 is the latest edition of this pioneering textbook. Updated to incorporate the recent major advances, Genomes 3 is an invaluable companion for any undergraduate throughout their studies in molecular genetics.

Genomes 3 builds on the achievements of the previous two editions by putting genomes, rather than genes, at the centre of molecular genetics teaching. Recognising that molecular biology research was being driven more by genome sequencing and functional analysis than by research into genes, this approach has gathered momentum in recent years.

  

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Genomes

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This undergraduate textbook concentrates on the study of the genome (the total genetic makeup of an organism) as a whole rather than the traditional approach of studying specific genes. The writing is ... Read full review

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Contents

Studying Genomes
1
Genomes Transcriptomes and Proteomes 3
24
Study Aids
32
1
34
14
42
Mapping Genomes
63
2
64
Any unique DNA sequence can be used as an STS
92
Study Aids
327
Synthesis and Processing
333
Synthesis and Processing of RNA
334
48
374
Synthesis and Processing of the Proteome
385
51
387
Regulation of Genome Activity
424
Synthesis and Processing of the 14 1 2 Signal transmission mediated by cell surface
429

3
94
Sequencing Genomes
103
Assembly of a Contiguous DNA Sequence
112
Wholegenome shotgun sequencing
119
Understanding a Genome Sequence
134
Studv Aids
162
Understanding How a Genome Functions
167
Genome Anatomies
195
179
202
Study Aids
220
Genomes of Prokaryotes and Eukaryotic Organelles
225
Study Aids
244
Virus Genomes and Mobile Genetic Elements
249
Study Aids
264
How Genomes Function
269
Accessing the Genome
271
Study Aids
290
1 Assembly of the Transcription Initiation Complex 295
318
Study Aids
459
How Genomes Replicate and Evolve
465
Study Aids
499
Mutations and DNA Repair
505
Study Aids
535
Recombination
541
Study Aids
558
How Genomes Evolve
563
Study Aids
589
Molecular Phylogenetics
595
59
625
Appendix
627
67
652
Glossary
653
Index
683
611
693
68
700
Copyright

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About the author (2007)

Professor Terry Brown graduated from Queen Elizabeth College, London with a BSc Hons in Microbiology in 1974, and from University College London with a PhD in 1977. He joined the University of Manchester Institute of Science and Technology as a postdoctoral researcher in 1981, and has remained in Manchester ever since, becoming the UK's first Professor of Biomolecular Archaeology in 2000. He was Head of Biomolecular Sciences from 2002 - 2004 and has been Associate Dean in Life Sciences since 2004.

Terry Brown has been active in genomics and biomolecular archaeology since 1989. He is particularly interested in the origins and spread of agriculture and has published a number of research papers that describe how examination of the genomes of wheat and maize can provide information on the history of cultivation of these crops.

Bibliographic information