The Biology and chemistry of polyamines: proceedings of an Argentine-Japanese joint seminar, Buenos Aires, Argentina, April 9-12, 1989
This volume provides the latest information on the biology and chemistry of polyamines, which play a vital role in normal cellular development and disease. The leading international contributors examine the involvement of polyamines in metabolic regulation, mammalian cell growth and differentiation, the role of polyamines in microorganisms and viruses, and the design of polyamine analogues. As a compilation of current research, this volume will prove invaluable for researchers in molecular biology, pharmacology, microbiology, and oncology.
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2-methylputrescine 30S subunits addition adenylate cyclase AdoMetDC Algranati Alhonen-Hongisto alkylputrescines amino acid angiogenesis antizyme assayed Biochem Biol Biophys cDNA cell line cellular polyamine Chem cloned concentration cruzi culture cycloheximide db-cAMP decrease depletion DFMO effect of DFMO effects of polyamines enzyme Escherichia coli G-proteins GDPBS Gpp(NH)p growth HCMV hepatocytes Holtta human ODC gene hypomethylation ICSU Press Igarashi increase incubated induced infected inhibition inhibitors intracellular Janne lymphocytes mammalian meristematic metastases methylation mouse mutant Northern blot nucleotides ODC activity ODC mRNA level oncogene ornithine decarboxylase Oshima Pegg Persson phosphorylation polyamine biosynthesis polyamine content polyamine metabolism polyamine uptake polyamines presence protein synthesis putrescine putrescine and spermidine pyrrole radioactivity rat liver reaction regulation ribosomal protein role root sequence shown spermidine and spermine spermidine synthase spermine stimulation Sunkara TABLE Tabor temperature thermine thermophile tissues transcription transfected transformed cells treatment tumor cells Tyms vitro vivo