Factor VIII - von WIllebrand Factor, Volume 1
In volume I (Subtitled: Biochemical, methodological and functional aspects), the purification and structure/function relationships of VIII and vWf are extensively reviewed with the relevance of advances in these areas to improved methodology and biotechnology. Emphasis is on the importance of improved interactions with plasmatic and cellular components. The issues of plasma procurement and advances in the production of therapeutic products illustrate application. An update of progress in the clinical aspects of VIII and vWf deficiency states is presented in Volume II (Subtitled: Clinical aspects of deficiency states; 6829-4). The critical issues of scientific advancement and achievement are shown to result in improved patient diagnosis and care. Annotation copyrighted by Book News, Inc., Portland, OR
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Interaction of Cell Proteases with Factor VIII and VWf
Electron Microscopic Studies of v Wf in Platelets and Megakaryocytes 201
Appendix Nomenclature and Abbreviations 325
abnormal acquired immunodeficiency syndrome activity AIDS antigen assay assessment biopsy bleeding episodes blood products carriers chronic Clin clinical concentrates clotting factor coagulation cryoprecipitate DDAVP deformity detection disorders donor dose effects factor concentrates factor IX factor IX concentrates factor replacement factor VIII factor VIII concentrates factor VIII inhibitor fetal fibrinogen fibronectin Figure flexion fractionation gene genetic Haematol Haemostasis heat-treated hemarthrosis hematoma hemophilia hemophilic arthropathy hemophilic patients hemorrhage hepatitis HIV infection immune complexes inactivation increased infusion joint knee Lancet levels liver disease Mannucci method molecular multimeric multimers muscle nerve Nilsson normal patients with hemophilia plasma platelet Pneumocystis carinii pneumonia polymorphism prenatal diagnosis present probe problems procedures protein prothrombin complex concentrates pseudotumor reported response risk ristocetin soft tissue surgery symptoms therapeutic therapy Thromb thrombin thrombogenicity titer transfusion treatment VHI/vWf VIII deficiency VIII:C viral virus vitro vivo vWf:Ag Willebrand factor Willebrand's disease