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Abuse and Habitual Academy of Engineering Academy of Sciences activities applicants for treatment applied clinical research basic research program Behavioral and Social Committee on Substance control group control procedures Department of Psychology downtown drunks drug abuse treatment drug problem established evaluation field replication research field replication studies Gerstein goals Habitual Behavior history of drug identified Implementation Studies important innovative treatments Institute of Medicine Institute on Drug investigators involved Kandel LOUIS LASAGNA management information system methods National Academy National Research Council null hypothesis number of communities outcome measures populations Process measures program information program managers Public Policy Analysis recommend that NIDA recruitment replication projects research advances responsibility review groups schizophrenia scientific standards service delivery unit Social Sciences STUDIES ON SUBSTANCE substance abuse treatment tested tobacco smoking treatment for drug treatment innovation treatment of substance treatment program treatment research trial types of studies University University of Pennsylvania