Idiopathic dilated cardiomyopathy: cellular and molecular mechanisms, clinical consequences
The latest developments in molecular biology have broadened our understanding of the pathogenesis of idiopathic dilated cardiomyopathy (IDC). In this book, written by well-known experts, a comprehensive overviewof IDC is given, including basic cellular and molecular concepts, virology, immunology, cardiac receptors and ionic channels, contractility abnormalities, microcirculation, and oxygen supply in cardiac hypertrophy. Details on basic research are supplemented by results of new clinical trials in IDC and the latest data on the epidemiology of the disease. For those who are interested in the disease, the book summarizes progress in all major fields.
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Natural History of Idiopathic Dilated Cardiomyopathy
Molecular Analysis of Cardiac Growth and Development
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abnormalities activity acute adenylate cyclase adrenergic adrenergic receptor adrenoceptors agonist antibodies antigens antimyosin arterial binding Biol biopsy blockers Ca2+ calcium channel capillary cardiac hypertrophy cardiac myocytes Cardiovasc cellular chronic Circ Res Circulation Clin clinical Coll Cardiol collagen congestive cardiomyopathy congestive heart failure contractile coronary flow coxsackievirus coxsackievirus B3 CVB2 CVB3 decreased detected diastolic effects ejection fraction endomyocardial biopsy enterovirus enterovirus infection expression Figulla function G protein gene growth factors hamster heart disease heart muscle hemodynamic human myocardium hybridization hypertension idiopathic dilated cardiomyopathy increased inositol inotropic intracellular kinase left ventricle left ventricular hypertrophy lesions mechanisms membrane mice molecular murine myocardial cells myocardial oxygen consumption myocardium myopathic myosin Na+ channels necrosis normal Olsen EGJ overload patients Pharmacol Physiol potential pressure receptor response role sarcoplasmic skeletal muscle Sonnenblick EH specific stimulation studies Suppl systolic therapy tissue viral myocarditis virus vitro vivo Xamoterol