Glial Neurobiology (Google eBook)

Front Cover
John Wiley & Sons, Aug 20, 2007 - Medical - 230 pages
1 Review
"This volume is a very valuable and much needed contribution." –Quarterly Review of Biology

AT LAST - A comprehensive, accessible textbook on glial neurobiology!

Glial cells are the most numerous cells in the human brain but for many years have attracted little scientific attention. Neurophysiologists concentrated their research efforts instead, on neurones and neuronal networks because it was thought that they were the key elements responsible for higher brain function. Recent advances, however, indicate this isn’t exactly the case. Not only are astroglial cells the stem elements from which neurones are born, but they also control the development, functional activity and death of neuronal circuits. These ground-breaking developments have revolutionized our understanding of the human brain and the complex interrelationship of glial and neuronal networks in health and disease.

Features of this book:

  • an accessible introduction to glial neurobiology including an overview of glial cell function and its active role in neural processes, brain function and nervous system pathology
  • an exploration of all the major types of glial cells including: the astrocytes, oligodendrocytes and microglia of the ACNS and Schwann cells of the peripheral nervous system; the book also presents a broad overview of glial receptors and ion channels
  • an investigation into the role of glial cells in various types of brain diseases including stroke, neurodegenerative diseases such as Alzheimer's, Parkinson's and Alexander's disease, brain oedema, multiple sclerosis and many more
  • a wealth of illustrations, including unique images from the authors' own libraries of images, describing the main features of glial cells

Written by two leading experts in the field, Glial Neurobiology provides a concise, authoritative introduction to glial physiology and pathology for undergraduate/postgraduate neuroscience, biomedical, medical, pharmacy, pharmacology, and neurology, neurosurgery and physiology students. It is also an invaluable resource for researchers in neuroscience, physiology, pharmacology and pharmaceutics.

  

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Review: Glial Neurobiology

User Review  - Carolyn - Goodreads

Only 10% of the entire nervous system exists as neurons, yet these cells are the first things we imagine when we're asked to think of the brain on a biological level. So what makes up the remaining 90 ... Read full review

Contents

Part I Physiology of Glia
1
1 Introduction to Glia
3
2 General Overview of Signalling in the Nervous System
13
3 Morphology of Glial Cells
21
4 Glial Development
29
5 General Physiology of Glial Cells
39
6 NeuronalGlial Interactions
83
PART II Glial Cells and Nervous System Function
93
8 Oligodendrocytes Schwann Cells and Myelination
125
PART III Glia and Nervous System Pathology
153
9 General Pathophysiology of Glia
155
10 Glia and Diseases of the Nervous System
167
Conclusions
197
Recommended literature
199
Author Index
207
Subject Index
209

7 Astrocytes
95

Common terms and phrases

About the author (2007)

Alexei Verkhratsky is Professor of Neurophysiology and Chairman of the Division of Neuroscience at the University of Manchester, UK

Arthur Butt is Professor of Cellular Neurophysiology, Department of Pharmacy and Biomedical Sciences, University of Portsmouth, UK.

Bibliographic information