Marks' basic medical biochemistry: a clinical approach

Michael Lieberman, Allan D. Marks

Lippincott Williams & Wilkins, 2009 - Medical - 1011 pages

A best-selling core textbook for medical students taking medical biochemistry, Marks' Basic Medical Biochemistry links biochemical concepts to physiology and pathophysiology, using hypothetical patient vignettes to illustrate core concepts. Completely updated to include full-color art, expanded clinical notes, and bulleted end-of-chapter summaries, the revised Third Edition helps medical students understand the importance of the patient and bridges the gap between biochemistry, physiology, and clinical care.

A new companion Website will offer the fully searchable online text, an interactive question bank with 250 multiple-choice questions, animations depicting key biochemical processes, self-contained summaries of patients described in the book, and a comprehensive list of disorders discussed in the text, with relevant Website links. An image bank, containing all the images in the text, will be available to faculty.

What people are saying

User Review -

As a medical student, I really benefited a lot from this book. Found all the necessary information required in a simple way. What makes it special is the nice diagrams and clinical case scenarios provided in each chapter.

User Review -

I'm studying medicine, and our biochem lecturer usually tends to use strangely scary diagrams to explain a simple concept, and its always confusing for everyone. But with this book, I got a good grasp of essential biochem for medicine. Give it a try

Contents

• Contents SECTION ONE Fuel Metabolism: 1
• Metabolic Fuels and Dietary Components: 3
• The Fed or Absorptive State: 22
• Fasting31: 31
• SECTION TWO Chemical and Biologic Foundations of Biochemistry: 41
• Water Acids Bases and Buffers: 53
• Structures of the Major Compounds of the Body: 56
• Amino Acids in Proteins: 73
• StructureFunction Relationships in Proteins: 92
• Enzymes as Catalysts: 116
• Regulation of Enzymes: 139
• Relationship between Cell Biology and Biochemistry: 156
• Cell Signaling by Chemical Messengers: 176
• SECTION THREE Gene Expression and the Synthesis of Proteins: 197
• Structure of the Nucleic Acids: 199
• Synthesis of DNA: 216
• Synthesis of RNA: 233
• Synthesis of Proteins: 254
• Regulation of Gene Expression: 271
• Use of Recombinant DNA Techniques in Medicine: 297
• The Molecular Biology of Cancer: 316
• SECTION FOUR Fuel Oxidation and the Generation of ATP: 337
• ATP and O2: 341
• Tricarboxy lie Acid Cycle361: 361
• Oxidative Phosphorylation and Mitochondrial Function: 383
• Glycosis: 402
• Oxidation of Fatty Acids and Ketone Bodies: 423
• Oxygen Toxicity and FreeRadical Injury: 443
• Metabolism of Ethanol: 464
• SECTION FIVE Carbohydrate Metabolism: 479
• Basic Concepts in the Regulation of Fuel Metabolism by Insulin Glucagon and Other Hormones: 483
• Digestion Absorption and Transport of Carbohydrates: 499
• Formation and Degradation of Glycogen: 518
• Pentose Phosphate Pathway Fructose and Galactose Metabolism: 536
• Synthesis of Glycosides Lactose Glycoproteins and Glycolipids: 551
• Gluconeogenesis and Maintenance of Blood Glucose Levels: 566
• SECTION SIX Lipid Metabolism: 591
• Digestion and Transport of Dietary Lipids: 593
• Synthesis of Fatty Acids Triacylglycerols and the Major Membrane Lipids: 605
• Cholesterol Absorption Synthesis Metabolism and Fate: 634
• Metabolism of the Eicosanoids: 671
• Integration of Carbohydrate and Lipid Metabolism: 685
• SECTION SEVEN Nitrogen Metabolism: 701
• Protein Digestion and Amino Acid Absorption: 705
• Urea Cycle: 715
• Synthesis and Degradation of Amino Acids: 733
• Tetrahydrofolate Vitamin B12 and SAdenosylmethionine: 751
• Purine and Pyrimidine Metabolism: 766
• Intertissue Relationships in the Metabolism of Amino Acids: 783
• SECTION EIGHT Tissue Metabolism: 803
• Actions of Hormones That Regulate Fuel Metabolism: 805
• Biochemistry of Erythrocytes and Other Blood Cells: 831
• Blood Plasma Proteins Coagulation and Fibrinolysis: 854
• Liver Metabolism: 870
• Metabolism of Muscle at Rest and During Exercise: 891
• Metabolism of the Nervous System: 911
• The Extracellular Matrix and Connective Tissue: 936
• Answers to Review Questions: 954
• Index: 979

Bibliographic information

• Title: Marks' basic medical biochemistry: a clinical approach; Point (Lippincott Williams and Wilkins) Series
• Authors: Michael Lieberman, Allan D. Marks
• Edition: 3, illustrated
• Publisher: Lippincott Williams & Wilkins, 2009
• ISBN: 078177022X, 9780781770224
• Length: 1011 pages
• Subjects: Medical / Biochemistry; Medical / Pharmacy; Medical / Test Preparation & Review