Serotonin, Sleep and Mental DisorderC. Idzikowski, Christopher Idzikowski, P. J. Cowen This volume addresses the complex question - What is the relationship between sleep, neurotransmitter function and mental state? Contributors review recent research into the neurotransmitter serotonin, its receptors, binding sites, electrophysiology and behavioural effects, as well as reviewing current ideas on the structure and function of human sleep. |
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Contents
An Introduction to Serotonin Sleep and Mental Disorder | 3 |
Evidence Supporting the Role | 5 |
Receptors and Subtypes | 9 |
Copyright | |
16 other sections not shown
Common terms and phrases
5-hydroxytryptamine 5HT evoked 5HT₂ 5HT2 antagonist 5HT2 receptors 5HTP 8OH-DPAT acid action activity Aghajanian agonist Andrade and Nicoll animal models antagonism antidepressant anxiogenic anxiolytic aversive baseline behaviour benzodiazepines binding Biochem Brain Res buspirone cells cholinergic chronic Clin clinical clomipramine Colpaert Cowen Decrease depolarization depressed patients dopamine dorsal raphe dose drugs Dugovic effects of ritanserin function haloperidol hippocampus hormone hyperpolarization Idzikowski imipramine increased induced inhibition insomnia interaction intracellular involved Janssen ketanserin mCPP mechanisms mediated Meert melatonin membrane mental disorder metergoline methysergide mg/kg models of anxiety modulation motoneurones neuroleptics neurones Neurosci neurotransmitter noradrenaline nucleus panic disorder Pharmacol pharmacological placebo potential prolactin prolactin responses Psychiatry Psychopharmacology raphe nuclei release REM latency REM sleep risperidone ritanserin role schizophrenia selective serotonergic serotonergic agents serotonin receptors sleep deprivation slow wave sleep stimulation studies subtypes suppression SWS2 symptoms TFMPP treatment triazolam tryptophan vitro voltage wakefulness X-maze