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abnormality acute ulcerative gingivitis aetiology affected amphotericin antibiotic antibodies aphthous ulceration associated attack become biopsy black hairy tongue blood examination buccal mucosa bulla candida carcinoma cause colour condition corium dental practice dental practitioner denture denture sore mouth differential diagnosis disease drug early epithelium essential excision factor fibrous epulis filiform papilla fissures generalised gingivitis glands hairy tongue herpes histological histological examination hydrocortisone hyperplastic inflammatory investigation involved irritation keratin keratinisation layer lead lesions leukoplakia lichen planus minor aphthous ulceration mouthwash naevus necessary neoplasm non-specific normal nystatin occasionally occur onset oral hygiene oral lesions oral medicine oral mucosa oral symptoms oral ulceration overgrowth painful palate parakeratosis pemphigus periodontal Pindborg pre-malignant pregnancy prognosis rarely reaction recognised recurrent result saliva salivary secondary infection skin smear soft tissues specific steroid surface syphilis systemic steroids tetracycline therapy tion tobacco trauma treatment tumour usually vascular Vincent's organisms viral infections virus white patch